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Paper | Special issue | Vol 82, No. 1, 2010, pp.333-338
Published online, 10th February, 2010
DOI: 10.3987/COM-10-S(E)3
Amphidinolide C3, a New Cytotoxic 25-Membered Macrolide from Marine Dinoflagellate Amphidinium sp

Takaaki Kubota, Akiko Suzuki, Mika Yamada, Shigeyuki Baba, and Jun'ichi Kobayashi*

*Graduate School of Pharmaceutical Sciences, Hokkaido University, Kita 12 Nishi 6, Kita-ku, Sapporo, Hokkaido 060-0812, Japan


A new cytotoxic 25-membered macrolide, amphidinolide C3 (1), has been isolated from marine dinoflagellate Amphidinium sp. (Y-56 strain), and the structure of 1 was elucidated on the basis of spectroscopic data and chemical means.