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Note | Regular issue | Vol 81, No. 3, 2010, pp.689-698
Published online, 8th January, 2010
DOI: 10.3987/COM-09-11865
The First Cerium (IV) Ammonium Nitrate (CAN)-Catalyzed Friedländer Synthesis of Quinolines in Ionic Liquid

Rei-Sheu Hou,* Huey-Min Wang, Iou-Jiun Kang, Hau-Dung Du, and Ling-Ching Chen*

*Department of Cosmetic Science, Chung Hwa University of Medical Technology, Department of Chemistry, National Cheng Kung University, Tainan, 701, Taiwan, R.O.C.


A mild and efficient route for the synthesis of quinolines and polycyclic quinolines utilizing cerium (IV) ammonium nitrate (CAN) as a novel catalyst via Friedländer annulation in ionic liquid 1-n-butyl-3-methylimidazolium hexafluorophosphate [Bmim][PF6] under mild conditions was described.