HETEROCYCLES
An International Journal for Reviews and Communications in Heterocyclic ChemistryWeb Edition ISSN: 1881-0942
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Note | Regular issue | Vol 78, No. 9, 2009, pp.2337-2342
Published online, 30th April, 2009
Published online, 30th April, 2009
DOI: 10.3987/COM-08-11353
■ Caro’s Acid-Silica Gel Catalyzed Synthesis of 2-Aryl-1H-Benzimidazoles and 2-Aryl-1-arylmethyl-1H-benzimidazoles
Ali A. Mohammadi,* Javad Azizian, and Narges Karimi
*Department of Chemistry, Faculty of Science, Islamic Azad University, Sabzevar 9618814711, Iran
Abstract
An efficient procedure for the synthesis of 2-aryl-1H-benzimidazoles and 2-aryl-1-arylmethyl-1H-benzimidazoles has been developed by simple condensation of o-phenylenediamine and aromatic aldehyde in the presence of Caro's acid supported on silica gel in ethanol under reflux.
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