Online article for Non-subscribers

Pay per view

Heterocycles has a pay-per-view service for Non-subscribers.
You will be able to directly purchase the full text article through PayPal.
Your purchased Paper can be downloaded after the payment is completed.
An e-mail will be sent the URL to download the paper.
If you have any questions, please contact:

Price: ¥ 4,400 (Yen only)
Period: This Article can be accessed for 7 days.

Paper | Regular issue | Vol 78, No. 3, 2009, pp.699-706
Published online, 12th November, 2008
DOI: 10.3987/COM-08-11559
An Efficient Single Step Synthesis of Pyridazine, Pyrazolo[5,1-c]-1,2,4-triazine, 1,2,4-Triazolo[5,1-c]-1,2,4-triazine and 1,2,4-Triazino[4,3-a]benzimidazole Derivatives

Mohamed R. Shaaban, Tamer S. Saleh, and Ahmad M. Farag*

*Department of Chemistry, Faculty of Science, University of Cairo, Giza 12613, Egypt


Coupling of E-1-(1-methylbenzimidazol-2-yl)-3-(N,N-dimethylamino)prop-2-enone (1) with the arenediazonium salt gave hydrazonopropanal 5 which underwent cyclocondensation with active methylene compounds to afford substituted pyridazin-6-imine 8 and 11. The enaminone 1 coupled also with the diazonium salts prepared from aminopyrazole, aminotriazole and 2-amino-1H-benzimidazole to afford pyrazolo[5,1-c]-[l,2,4]-triazine 15, 1,2,4-triazolo[5,1-c]-[1,2,4]-triazine 19, 1,2,4-triazino[4,3-a]benzimidazole 23 derivatives, respectively.