HETEROCYCLES
An International Journal for Reviews and Communications in Heterocyclic ChemistryWeb Edition ISSN: 1881-0942
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Note | Regular issue | Vol 78, No. 2, 2009, pp.487-493
Published online, 16th October, 2008■ An Efficient Protocol for the Friediänder Synthesis of Quinolines Using the Lewis Acidic Ionic Liquid Choline Chloride·2ZNCL2
Published online, 16th October, 2008
DOI: 10.3987/COM-08-11516
■ An Efficient Protocol for the Friediänder Synthesis of Quinolines Using the Lewis Acidic Ionic Liquid Choline Chloride·2ZNCL2
Huey-Min Wang,* Rei-Sheu Hou, Hui-Ting Cheng, and Ling-Ching Chen*
*Graduate Institute of Pharmaceutical Sciences, College of Pharmacy, Kaohsiung Medical University, Kaohsiung 807, Taiwan, R.O.C.
Abstract
Lewis acidic ionic liquid choline chlorideÅE2ZnCl2 is shown to be for the first time an excellent solvent and efficient catalyst for the synthesis of quinolines via Friedländer annulation under mild conditions.
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