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Communication | Special issue | Vol 79, No. 1, 2009, pp.303-309
Published online, 4th August, 2008
DOI: 10.3987/COM-08-S(D)3
Palladium-catalyzed Arylation at C-H and C-C Bonds of Masked Thiazole Derivatives

Hirotoshi Furukawa, Suguru Matsumura, Atsushi Sugie, Daiki Monguchi, and Atsunori Mori*

*Department of Chemical Science and Engineering, Kobe University, 1-1 Rokkodai, Nada, Kobe 657-8501, Japan

Abstract

The differently substituted 2,5-diarylthiazole derivatives are synthesized via palladium catalyzed sequential C-H arylation at the 5-position and C-C bond activation at the 2-positon with masked thiazole.