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Communication | Special issue | Vol 17, No. 1, 1982, pp.155-158
Published online, 1st January, 1970
DOI: 10.3987/S-1982-01-0155
Structure of Ephedradine D, a Hypotensive Principle of Ephedra Roots

Hiroshi Hikino,* Minoru Ogata, and Chohachi Konno

*Pharmaceutical Institute, Tohoku University, Aramaki, Aoba-ku, Sendai 980-8578, Japan


From the crude drug “mao-kon”, the roots of Ephedra plants, a new macrocyclic spermine alkaloid ephedradine D exhibiting the hypotensive activity has been obtained whose stereostructure has been elucidated as shown in formula I based on chemical and physical evidence.