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Communication | Special issue | Vol 17, No. 1, 1982, pp.99-103
Published online, 1st January, 1970
DOI: 10.3987/S-1982-01-0099
The Partial Syntheses of Reserpiline and Isoreserpiline

Shin-ichiro Sakai,* Naoki Saito, Naohiro Hirose, and Etsuji Yamanaka

*Faculty of Pharmaceutical Sciences, Chiba University, 1-33 Yayoi-cho, Inage-ku, Chiba 263-8522, Japan


Reserpiline 4 and isoreserpiline 3 were first synthesized through 5,6-dimethoxyindole derivative 11, 12 and amine synthon 8 which was already derived from natural oxindole alkaloids 9, 10 and/or by the total syntheses.