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Communication | Special issue | Vol 15, No. 1, 1981, pp.201-206
Published online, 1st January, 1970
DOI: 10.3987/S-1981-01-0201
Total Synthesis of (±)-Eburnamonine and (±)-Epieburnamonine

Kunihiko Irie and Yoshio Ban*

*Faculty of Pharmaceutical Sciences, Hokkaido University, Kita 12 Nishi 6, Kita-ku, Sapporo, Hokkaido 060-0812, Japan


Anodic oxidation of N-carbomethoxy-3-ethylpiperidine-3-acetic acid (11) provided the corresponding lactone (12) in good yield, from which were synthesized (±)-eburnamonine and (±)-epieburnamonine by the modified procedure.