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Communication | Special issue | Vol 15, No. 1, 1981, pp.165-177
Published online, 1st January, 1970
DOI: 10.3987/S-1981-01-0165
Novel Condensing Agents for Bischler-Napieralski Type Cyclodehydration

Sreeramulu Nagubandi* and G. Fodor

*Mayo Clinic and Mayo Foundation, Rochester, Minesota 55901, U.S.A.


Trifluoroaceticanhydride and trifluoromethyl sulfonyl anhydride are used in Bischler-Napieralski type cyclization. Starting from the appropriate amides, the dihydroisoquinolines are formed in excellent yields.