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Communication | Special issue | Vol 13, No. 1, 1979, pp.221-225
Published online, 1st January, 1970
DOI: 10.3987/S-1979-01-0221
Carbon Transfer via N5, N10-Methylenetetrahydrofolate Models

H. Bieräugel, R. Plemp, H.C. Hiemstra, and U.K. Pandit*

*Organic Chemistry Laboratory, University of Amsterdam, Nieuwe Achtergracht 129, 1018 WS Amsterdam, The Netherlands


1-Acyl or 1-tosyl-3,4,4-trimethylimidazolidine derivatives react with tryptamine or 2-(3,4-dimethoxyphenyl)ethylamine, under acidic conditions, to yield tetrahydro-β-carboline or tetrahydroisoquinoline derivatives.