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Communication | Special issue | Vol 10, No. 1, 1978, pp.159-165
Published online, 1st January, 1970
DOI: 10.3987/S-1978-01-0159
Biogenetic Type Synthesis of Blepharismone, a Conjugation Inducing Gamone in Ciliate Bleparisma

Takashi Tokoroyama,* Yoshinori Kawasaki, Miwako Nakatani and Kozo Shibata

*Faculty of Pharmaceutical Science, Osaka City University, Sugimoto, Sumiyoshi-ku, Osaka 558-8585, Japan

Abstract

Blepharismone 1 was synthesized by oxidation of benzyl 5-benzyloxyindolyllactate 5 followed by deprotection, which was prepared by the reaction of 5-benzyloxyindolylmagnesium iodide 9 with benzyl glycidate 7.