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Communication | Special issue | Vol 10, No. 1, 1978, pp.133-138
Published online, 1st January, 1970
DOI: 10.3987/S-1978-01-0133
Synthesis of β-Hydroxy-α-amino Acids by Substitution Reactions of Thiazoline and Imidazoline Compounds

Tetsuo Shiba,* Kozo Sawada, and Yoshihiro Hirotsu

*Department of Chemistry, Faculty of Science, Osaka University, Toyonaka, Osaka 560-8531, Japan


β-Hydroxy-α-amino acids were newly synthesized by the aldol condensation of 2-benzyloxycarbonylaminomethyl-2-thiazoline (II) or -2-imidazoline (VI) with aldehydes followed by acid hydrolysis.