Online article for Non-subscribers

Pay per view

Heterocycles has a pay-per-view service for Non-subscribers.
You will be able to directly purchase the full text article through PayPal.
Your purchased Paper can be downloaded after the payment is completed.
An e-mail will be sent the URL to download the paper.
If you have any questions, please contact:

Price: ¥ 4,400 (Yen only)
Period: This Article can be accessed for 7 days.

Communication | Special issue | Vol 7, No. 2, 1977, pp.891-894
Published online, 1st January, 1970
DOI: 10.3987/S-1977-02-0891
Isolation of 1-Methyl-4,5-dibromopyrrole-2-carboxylic Acid and Its 3’-(Hydantoyl)propylamide (Midpacamide) from a Marine Sponge

Lionel Chevolot, Steve Padua, B. N. Ravi, Peter C. Blyth, and Paul J. Scheuer*

*Department of Chemistry, University of Hawaii at Manoa, 2545 Tha Mall, Honolulu, Hawaii 96822-2275, U.S.A.


From an unidentified marine sponge collected in the Marshall islands we have isolated 1-methyl-4,5-dibromopyrrole-2-carboxylic acid (III) and its 3’-(hydantoyl)propylarmide, midpacamide (III). The acid was synthesized and the structure of the amide was determined by spectral analysis and by hydrolysis in alkaline and acid media.