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Communication | Special issue | Vol 8, No. 1, 1977, pp.103-108
Published online, 1st January, 1970
DOI: 10.3987/S(S)-1977-01-0103
Chemical Transformation of α-Santonin into Balchanin, Colartin, and Arbusculin A, B, C, and E

Koji Yamakawa,* Kiyoshi Nishitani, and Kazutoyo Azusawa

*Faculty of Pharmaceutical Sciences, Science University of Tokyo, 2641 Yamazaki, Noda, Chiba 278-8510, Japan


Some sesquiterpene α-methylene-γ-lactones are worthy of attention for their biological activities. The chemical transformation of santonin into sesquiterpene α-methylene-γ-lactones, balchanin, arbusculin A, B, C, and E, and their precursor, colartin, is described.