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Communication | Special issue | Vol 18, No. 1, 1982, pp.47-49
Published online, 1st January, 1970
DOI: 10.3987/S(B)-1982-01-0047
Fuziline, a New Alkaloid from the Chinese Drug “Fuzi” (Aconitum carmichae Debx.)

S. W. Pelletier,* Naresh V. Mody, Kottayil I. Varughese, and Chen Szu-Ying

*Department of Medical Chemistry and Pharmacognosy, College of Pharmacy, The University of Georgia, Athens, Georgia 30602, U.S.A.

Abstract

Chemical investigation of the famous Chinese drug “Fuzi” (Aconitum carmichaeli Debx) resulted in the isolation of a new alkaloid, fuziline, along with the known alkaloids, aconitine, hypaconitine, mesaconitine, neoline and songorine. The structure of fuziline (1) has been established by the use of carbon-13 and proton NMR spectroscopy. Subsequently this structure was confirmed by a single-crystal X-ray analysis.