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Paper | Special issue | Vol 30, No. 2, 1990, pp.1031-1077
Published online, 1st January, 1970
DOI: 10.3987/REV-89-SR7
Synthesais of Corynanthe Alkaloids Corynantheine, Hirsuteine, and the Isositsirkines

Ichiya Ninomiya,* Takeaki Naito, Okiko Miyata,Tetsuro Shinada, Ekkehard Winterfeldt,* Ralf Freund, and Toshimasa Ishida

*Kobe Women’s College of Pharmacy, Motoyamakita, Higashinad, Kobe, Hyogo 658, Japan


Total syntheses of corynanthe alkaloids including eight possible stereoisomers of isositsirikines along with corynantheine and hirsuteine according to two different approaches are described, thereby unambiguously solved the pending problems on the stereochemitry of these alkaloids.