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Review | Regular issue | Vol 29, No. 7, 1989, pp.1409-1429
Published online, 1st January, 1970
DOI: 10.3987/REV-89-408
Synthesis of Pyrimidine Derivatives and Their Related Compounds Using Ketene Dithioacetals

Yoshinori Tominaga,* Shinya Kohra, Harumasa Honkawa, and Akira Hosomi

*Faculty of Pharmaceutical Sciences, Nagasaki University, 1-14, Bunkyo-machi, Nagasaki 852-8521, Japan


Ketene dithioacetals bearing electron-with-drawing groups are useful and versatile reagents for the synthesis of pyrimidine derivatives. This review article describes the synthetic usefulness and importance of ketene dithioacetals in the preparation of pyrimidines and fused pyrimidine derivatives.