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Review | Special issue | Vol 76, No. 2, 2008, pp.909-922
Published online, 12th June, 2008
DOI: 10.3987/REV-08-SR(N)5
Catalytic Asymmetric Hydrogenation of 5-Membered Heteroaromatics

Ryoichi Kuwano*

*Department of Chemistry, Graduate School of Sciences, Kyushu University, 6-10-1 Hakozaki, Higashi-ku, Fukuoka, 812-8581, Japan

Abstract

Catalytic asymmetric hydrogenation of heteroaromatics had been a formidable issue in organic synthesis. However, the catalytic asymmetric hydrogenation has remarkably progressed during the past decade. This review surveys the recent progress of the asymmetric hydrogenation of 5-membered heteroaromatics, indoles, pyrroles, furans, and benzofurans.