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Review | Special issue | Vol 76, No. 1, 2008, pp.99-127
Published online, 26th May, 2008
DOI: 10.3987/REV-08-SR(N)3
Marchantiophyta (Liverworts): Rich Sources of Macrocyclic Bis(bibenzyls)

Yoshinori Asakawa,* Masao Toyota, Toshihiro Hashimoto, Motoo Tori, Fumihiro Nagashima, and Liva Harinantenaina

*Faculty of Pharmaceutical Sciences, Tokushima Bunri University, Yamashiro-cho, Tokushima 770-8514 Japan


The Marchantiophyta (liverworts) produce which show interesting biological activity such as antimicrobial, antifungal, antiobesity and muscle relaxing activity etc. and are of very valuable for the chemosystematic and evolutional study of the Marchantiophyta and pteridophytes. The isolation, identification, structural elucidation and total synthesis of these characteristic natural products and their biological activity are reviewed.