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Review | Special issue | Vol 67, No. 2, 2006, pp.823-837
Published online, 30th September, 2005
DOI: 10.3987/REV-05-SR(T)2
Phosphate Mimic of Nucleotides, Conformational Influences on the Ribofuranose Conformations

Arnaud Gautier

*IRCOF-UPRES A 6014, Faculty of Sciences, University of Rouen, Rue Tesnières, F-76821 Mont Saint Aignan Cedex, France


The influences of the modifications of the natural nucleotides is rationalized in terms of stereoelectronics effects. This article reviews the pseudorotation concept and the Generalized Karplus Type equation used to quantify the conformational behavior of ribofuranose in solution.