Online article for Non-subscribers

Pay per view

Heterocycles has a pay-per-view service for Non-subscribers.
You will be able to directly purchase the full text article through PayPal.
Your purchased Paper can be downloaded after the payment is completed.
An e-mail will be sent the URL to download the paper.
If you have any questions, please contact:

Price: ¥ 4,400 (Yen only)
Period: This Article can be accessed for 7 days.

Communication | Regular issue | Vol 26, No. 12, 1987, pp.3111-3114
Published online, 1st January, 1970
DOI: 10.3987/R-1987-12-3111
Studies of as-Triazine Derivatives. X. Addition Reaction of Phenylmagnesium Bromide with 1,2,4-Triazines

Shoetsu Konno, Mataichi Sagi, Nobuko Yoshida, and Hiroshi Yamanaka

*Pharmaceutical Institute, Tohoku University, Aobayama, Sendai 980-8578, Japan


The reaction of 1,2,4-triazine with phenylmagnesium bromide was investigated. Every position of 3, 5, and 6 in a 1,2,4-triazine ring is active in the addition reaction of Grignard reagents. Since 5-phenyl-1,2,4-triazine, 5,6-diphenyl-1,2,4-triazine, and 3,5,6-triaryl-1,2,4-triazine were obtained subsequently, it was comfirmed that the most active position was position 5 and the least active one was position 3.