Online article for Non-subscribers

Pay per view

Heterocycles has a pay-per-view service for Non-subscribers.
You will be able to directly purchase the full text article through PayPal.
Your purchased Paper can be downloaded after the payment is completed.
An e-mail will be sent the URL to download the paper.
If you have any questions, please contact: purchase@heterocycles.com

Price: ¥ 4,400 (Yen only)
Period: This Article can be accessed for 7 days.

Communication | Regular issue | Vol 26, No. 11, 1987, pp.2853-2856
Published online, 1st January, 1970
DOI: 10.3987/R-1987-11-2853
Reaction of 2,4-Diphenyl-1,3,5-triazine Derivatives with Nucleophiles

Hiroshi Yamanaka, Setsuya Ohba, and Shoetsu Konno

*Pharmaceutical Institute, Tohoku University, Aobayama, Sendai 980-8578, Japan

Abstract

The addition of hydrogen cyanide to 2,4-diphenyl-1,3,5-triazine (1) followed by spontaneous oxidation of the adduct gave 4,6-diphenyl-1,3,5-triazine-2-carbonitrile (4) in considerable yield. Similarly, 1 reacted with various active methylene compounds in the presence of sodium hydride to give the corresponding 2-substituted 4,6-diphenyl-1,3,5-triazines (8a-c). Additionally, the condensation of 2-chloro-4,6-diphenyl-1,3,5-triazine (2) with benzaldehyde in the presence of 1,3-dimethylbenzimidazolium iodide under basic conditions, gave the corresponding 2-benzoyl-1,3,5-triazine (9).