Online article for Non-subscribers

Pay per view

Heterocycles has a pay-per-view service for Non-subscribers.
You will be able to directly purchase the full text article through PayPal.
Your purchased Paper can be downloaded after the payment is completed.
An e-mail will be sent the URL to download the paper.
If you have any questions, please contact:

Price: ¥ 4,400 (Yen only)
Period: This Article can be accessed for 7 days.

Communication | Regular issue | Vol 26, No. 11, 1987, pp.2817-2822
Published online, 1st January, 1970
DOI: 10.3987/R-1987-11-2817
A Regioselective and Common Synthetic Method of Dihalogenoindoles and Its Application for the Total Syntheses of Marine Alkaloids, 4,6-Dibromo-, 4,6-Dibromo-2-methyl-, and 3,4,5-Tribromoindole

Toshiharu Ohta, Yoshinori Yamato, Hiroko Tahira, and Masanori Somei

*Faculty of Pharmaceutical Sciences, Kanazawa University, 13-1 Takara-machi, Kanazawa 920-0934, Japan


A regioselective and common synthetic method for indoles carrying two different kinds of halogens was developed and applied successfully to the total syntheses of marinealkaloids, 4,6-dibromo- and 3,4,5-tribromoindole. The first total synthesis of 4,6-dibromo-2-methylindole is also reported.