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Communication | Regular issue | Vol 26, No. 7, 1987, pp.1779-1782
Published online, 1st January, 1970
DOI: 10.3987/R-1987-07-1779
Synthesis of Depyrrolo Analogue of Reserpine

Okiko Miyata, Etsuko Doi, Takeaki Naito, and Ichiya Ninomiya

*Kobe Women’s College of Pharmacy, Motoyamakita, Higashinad, Kobe, Hyogo 658, Japan

Abstract

Depyrrolo analogue (19) of reserpine was synthesized via the route involving hydrocyanation reaction of the β-methoxyenone (7) followed by the Michael reaction of the α,β-unsaturated nitrile (11) with sodium methoxide.