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Paper | Regular issue | Vol 26, No. 6, 1987, pp.1521-1525
Published online, 1st January, 1970
DOI: 10.3987/R-1987-06-1521
Phenyl Isothiocynate-mediated Condensation of Aceturic/2-acetylaminocinnamic Acid with Aromatic Aldehydes

Archana Jain and Arya K. Mukerjee

*Department of Chemistry, Faculty of Science, Banaras Hindu University, Varanasi - 221005, India


One-flask synthesis of 4-arylmethylene-1-phenyl-2-styryl-2-imidazolin-5-ones (3) was achieved by the phenyl isothiocyanate-mediated condensation of aceturic/2-acetylaminocinnamic acid (1) with aromatic aldehydes (2). In the presence of salicylaldehyde (2d), the reaction of 1a and 5 led to the formation of 3-acetylaminocoumarin (4).