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Communication | Regular issue | Vol 26, No. 6, 1987, pp.1461-1466
Published online, 1st January, 1970
DOI: 10.3987/R-1987-06-1461
Ring Expansion of 4-Benzoyl-β-lactams

Benito Alcaide, Gema Domíngues, Angel Martín-Domenech, Joaquín Plumet, Angeles Monge, and Virginia Pérez-García

*Departamento de Química Orgánica, Facultad de Química, Universidad Complutense de Madridas, Ciudad Universitaria, E-28040 Madrid, Spain


Diastereomerically pure 4-benzoyl-β-lactams react with NaH/DMF in the presence of an alkyl halide to give 5-alkoxy-γ-lactams.