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Paper | Regular issue | Vol 26, No. 5, 1987, pp.1239-1249
Published online, 1st January, 1970
DOI: 10.3987/R-1987-05-1239
Synthesis of (±)-Praeruptorin A and Related Khellactone Derivatives

Swati Bal-Tembe, Dilip N. Bhedi, Noel J. de Souza, and Richard Helmut Rupp

*Department of Chemistry, Research Centre, Hoechst India Limited, Mulund, Bombay 400 080, India


The first synthesis of the pyranocoumarin natural product, (±)-praeruptorin A (= Pd-Ia), is described. A general method for the preparation of various khellactone derivatives is reported.