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Communication | Regular issue | Vol 26, No. 3, 1987, pp.641-644
Published online, 1st January, 1970
DOI: 10.3987/R-1987-03-0641
A New Synthetic Method of 6-Aryl- or Vinyl-substituted 2-Oxotetrahydro-1,3-oxazines

Takushi Kurihara, Tatsuya Terada, Yoshitaka Matsubara, and Ryuji Yoneda

*Faculty of Pharmaceutical Science, Osaka University of Pharmaceutical Sciences, 4-20-1 Nasahara, Takatsuki, Osaka 569-1094, Japan

Abstract

A novel transformation of benzylic or allylic hydroxy-substituted N-tert-butoxycarbonyl compounds by treatment with methanesulfonyl chloride in the presence of triethylamine into 2-oxotetrahydro-1,3-oxazines is described.