Online article for Non-subscribers

Pay per view

Heterocycles has a pay-per-view service for Non-subscribers.
You will be able to directly purchase the full text article through PayPal.
Your purchased Paper can be downloaded after the payment is completed.
An e-mail will be sent the URL to download the paper.
If you have any questions, please contact:

Price: ¥ 4,400 (Yen only)
Period: This Article can be accessed for 7 days.

Paper | Regular issue | Vol 26, No. 1, 1987, pp.141-146
Published online, 1st January, 1970
DOI: 10.3987/R-1987-01-0141
Synthesis of Diketonic Intermediates for the Total Syntheses of Dihydrojasmone, cis-Jasmone and dl-Muscone Starting from 1,n-Di(1-methyl-1H-imidazol-2-yl)-1,n-alkanedione

Shunsaku Ohta, Satoshi Hayakawa, Yoshimi Tamai, Teruyuki Yuasa, and Masao Okamoto

*Kyoto Pharmaceutical University, Misasagi, Yamashina, Kyoto 607-8414, Japan


2,15-Dihydroxy-2,15-di(1-methyl-1H-imidazol-2-yl) hexadecane (3) was obtained by treating 1,14-(1-methyl-1H-imidazol-2-yl)-1,14-tetradecadione (2b) with an excess of CH3MgI, while 1,4-di (1-methyl-1H-imidazol-2-yl)-4-trimethylsilyloxy-2-pentanone (6; R1 = TMS) was obtained by the similar treatment of 1,4-(1-methyl-1H-imidazol-2-yl)-1,4-butadione (2a) followed by trimethylsilylation. These products (3 and 6) were convertible into the known diketonic intermediates for the synthesis of dl-muscone, dihydrojasmone and cis-jasmone.