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Communication | Regular issue | Vol 26, No. 1, 1987, pp.85-90
Published online, 1st January, 1970
DOI: 10.3987/R-1987-01-0085
Studies on the Synthesis of Optically Active Azalactams

Haruo Matsuyama, Michio Kobayashi, and Harry H. Wasserman

*Department of Chemistry, Faculty of Science, Tokyo Metropolitan University, Hachioji, Tokyo 192-0397, Japan


The optically active nine-membered azalactam, (S)-(-)- 1,5-diaza-4-phenylcyclononan-2-one has been prepared starting with optically active (S)-(-)-β-phenyl-β-alanine methyl ester and 2-methoxypyrroline. Other studies with chiral esters of transcinnamic acid and piperidazine are reported.