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Report | Regular issue | Vol 24, No. 12, 1986, pp.3369-3372
Published online, 1st January, 1970
DOI: 10.3987/R-1986-12-3369
A Cyclisation Reaction of 2-Cyanomethylbenzothiazole with Acetylenic Compounds via Michael Addition

Dilip Konwar, Romesh Chandra Boruah, and Jagir Singh Sandhu*

*Division of Drug and Pharmaceutical Chemistry, Regional Research Laboratory, Jorhat 785 006, Assam, India

Abstract

2-Cyanomethylbenzothiazole (1) reacts with acetylenic compounds (2) under the influence of base in Michael fashion followed by cyclisation to afford fused pyrido[2,1-b]benzothiazole (3&4) in excellent yields. The products were characterized through elemental and spectral analyses.