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Paper | Regular issue | Vol 24, No. 11, 1986, pp.3163-3167
Published online, 1st January, 1970
DOI: 10.3987/R-1986-11-3163
Isoazadirolide, a New Tetranortriterpenoid from Azadirachta indica A. Juss (Meliaceae)

Salimuzzaman Siddiqui,* Bina Shaheen Siddiqui, Shaheen Faizi, and Tariq Mahmood

*H. E. J. Postgraduate Institute of Chemistry, University of Karachi, Karachi-75270, Pakistan


A new ring-C seco tetranortriterpenoid γ-hydroxybutenolide named as isoazadirolide, has been isolated from the acidic fraction of the fresh, undried, winter leaves of Azadirachta indica A.Juss (neem), along with a coumarin identified as scopoletin. The structures of these compounds have been established through chemical and spectral studies. It is the first instance of isolation of a coumarin from any of the various parts of neem tree.