Online article for Non-subscribers

Pay per view

Heterocycles has a pay-per-view service for Non-subscribers.
You will be able to directly purchase the full text article through PayPal.
Your purchased Paper can be downloaded after the payment is completed.
An e-mail will be sent the URL to download the paper.
If you have any questions, please contact:

Price: ¥ 4,400 (Yen only)
Period: This Article can be accessed for 7 days.

Communication | Regular issue | Vol 24, No. 10, 1986, pp.2735-2738
Published online, 1st January, 1970
DOI: 10.3987/R-1986-10-2735
Anomalous Witting Reaction of Aldonic Thioamide Derivatives. A New Mode of Thiazole Ring Formation

László Somogyi,* Pál Herczegh, and Gyula Batta

*Reseaech Group of Antibiotics, Hungarian Academy of Sciences, H-4010 Debrecen, Hungary


A new mode of thiazole ring formation and an unexpected acetoxy group elimination were observed as a result of the reaction of N-acetyl-per-O-acetylhexonic thioamides (1b and 2b) with ethoxycarbonylmethylenetriphenylphosphorane affording ethyl 2-(1’,5’-diacetoxy-penta-1’,3’-Z,E-dien-1’-yl)-4-methylthiazole-5-carboxylate (6).