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Communication | Regular issue | Vol 24, No. 8, 1986, pp.2085-2088
Published online, 1st January, 1970
DOI: 10.3987/R-1986-08-2085
Nitriles in Heterocyclic Synthesis: New Approaches for Synthesis of Pyrazoles, Izoxazoles and Pyrimidines

Nadia S. Ibrahim,* Ebtisam A. A. Hafez, and Raafat M. Mohareb

*Department of Chemistry, Faculty of Science, University of Cairo, Giza, Egypt


A variery of pyrazoles and aminoisoxazole were prepared from reaction of N-benzylidene cyanoethanoic hydrazide derivatives with hydrazines and hydroxylamine. A novel pyrimidine synthesis from reaction of ethyl cyanoacetate with the hydrazide is reported.