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Paper | Regular issue | Vol 24, No. 7, 1986, pp.1973-1976
Published online, 1st January, 1970
DOI: 10.3987/R-1986-07-1973
Hashish: Oxidation of Δ8-Tetrahydrocannabinol (THC); Synthesis of Δ8-THC-1,2-Dione and 2-Hydroxy-Δ8-THC

Hossein Hadjat-Kashani, Gali Lambert, Richard Duffley, and Raj Razdan*

*The SISA Institute for research Inc., 763D Concord Avenue, Cambridge, MA 02138, U.S.A.


The title compounds were synthesized from δ8-THC in yields of 65% and 63% respectively. The structure of 3 as a 1,2-dione was supported by NOE data. structural re-assignment of a previously isolated quinonoid-THC 4 is proposed.