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Zenichi Yoshida (1925-2023)
Zenichi Yoshida (1925-2023)
Professor. Zenichi Yoshida,
a member of the Honorary Advisors of HETEROCYCLES (1975-1998),
has passed away on May 4, 2023 at the age of 97.
I deeply express my regret over his death.
Kunio Ogasawara
Editor
May 11, 2023
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Paper | Regular issue | Vol 24, No. 5, 1986, pp.1331-1346
Published online, 1st January, 1970■ Synthesis of Optically Active 3-Mercaptopyrrolidine Derivatives. Synthetic Intermediates of Carbapenem RS-533 and Its Isomer
Published online, 1st January, 1970
DOI: 10.3987/R-1986-05-1331
■ Synthesis of Optically Active 3-Mercaptopyrrolidine Derivatives. Synthetic Intermediates of Carbapenem RS-533 and Its Isomer
Tomoyuki Shibata, Kimio Iino, and Yukio Sugimura*
*Chemical Research Laboratories and Analytical & Metabolic Research Laboratories, Sankyo Co., Ltd., 1-2-58 Hiromachi, Shinagawa-ku, Tokyo 140-8710, Japan
Abstract
The optically active 3-mercaptopyrrolidine derivatives(3a, 3b, 4a and 4b), which are synthetic intermediates of the carbapenem RS-533 (2a) and its isomer (2b), were synthesized by convenient and practical methods.
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