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Report | Regular issue | Vol 24, No. 5, 1986, pp.1279-1284
Published online, 1st January, 1970
DOI: 10.3987/R-1986-05-1279
Nitrogen Assisted Acetal Ring Clevage. Part II. Preparation of Synthons for Eburnamine-vincamine Alkaloids

Mauri Lounasmaa* and Arto Tolvanen

*Laboratory of Organic Chemistry, Helsinki University of Technology, P.O. Box 6100,FIN-02015 HUT, Espoo, Finland

Abstract

The cleavage of cyclic 3-substituted tetrahydropyridine acetals under the modified Polonovski reaction conditions is described. The method was applied to the preparation of a 1-formylindolo[2,3-a]quinolizidine derivative.