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Yoshito Kishi (1937-2023)
Yoshito Kishi (1937-2023)
Professor. Yoshito Kishi,
a member of the Honorary Editorial Associates of HETEROCYCLES,
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Kunio Ogasawara
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January 13, 2023
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Communication | Regular issue | Vol 24, No. 5, 1986, pp.1257-1260
Published online, 1st January, 1970■ Structure and Syntheses of SEN-125 and Oxotomaymycin
Published online, 1st January, 1970
DOI: 10.3987/R-1986-05-1257
■ Structure and Syntheses of SEN-125 and Oxotomaymycin
Miwako Mori,* Yasuhiro Uozumi, and Yoshio Ban
*Faculty of Pharmaceutical Sciences, Hokkaido University, Kita 12 Nishi 6, Kita-ku, Sapporo, Hokkaido 060-0812, Japan
Abstract
The structure of SEN-215 was determined as (11aS)(E)-2-ethylidene-2,3,5,10,11,11a-hexahydro-8-hydroxy-7-methoxy-5-oxo-1H-pyrrolo[2,1-c][1,4]benzodiazepine by conversion of (E)- and (Z)-pretomaymycin into (E)- and (Z)-SEN-215.
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