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Communication | Regular issue | Vol 24, No. 5, 1986, pp.1231-1232
Published online, 1st January, 1970
DOI: 10.3987/R-1986-05-1231
Reduction of N-Alkoxycarbonyllactams with NaBH4/EtOh-H+: A Facile Synthesis of α-Ethoxyurethanes

Tatsuo Nagasaka,* Hirohisa Tamano, and Fumiko Hamaguchi

*School of Pharmacy, Tokyo University of Pharmacy and Life Science,1432-1 Horinouchi, Hachioji, Tokyo 192-0392, Japan


Reduction of N-alkoxycarbonyllactams with NaBH4/H+ in ethanol (Speckamp’s condition) afforded α-ethoxyurethanes (Shono’s compounds) in good yields.