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Communication | Regular issue | Vol 24, No. 5, 1986, pp.1227-1230
Published online, 1st January, 1970
DOI: 10.3987/R-1986-05-1227
(+)-Roemearine, a C-4 Hydroxylated Tetrahydrobenzylisoquinoline Alkaloid

Tekant Gözler,* Belkis Gözler, Nevin Tanker, Alan J. Freyer, Hélène Guinaudeau, and Maurice Shamma

*Department of Chemistry, The Pennsylvania State University, York Campus, P1031 Edgecomb Avenue, York, Pennsylvania 17403, U.S.A.


Roemeria carica A. Baytop (Papaveraceae) of Turkish origin has supplied (+)-roemecarine (1), which is the first C-4 hydroxylated tetrahydrobenzylisoquinoline alkaloid. Species 1 is accompanied in the plant extract by its N-oxide, (+)-roemecarine 2-α-N-oxide (4).