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Paper | Regular issue | Vol 24, No. 3, 1986, pp.679-686
Published online, 1st January, 1970
DOI: 10.3987/R-1986-03-0679
Synthesis of 2-Mercapto- and 2-Methylthio- Dihydropyrimidine Derivatives by Biguinelli Type Reaction

M. Velpuesta Fernández,* F. J. Herrera, and T. Lupión Cobos

*Departamento de Quimica Organica, Facultad de Ciencias, Universidad de Málaga, Campus de Teations, E-29071 Malaga, Spain

Abstract

The preparation of 6-(2,2-dimethyl-1,3-dioxolan-4-yl)-4-methyl-5-methoxycarbonyl-2-thio-1,2,3,6-tetrahydropyrimidine (1) and 6-(2,2-dimethyl-1,3-dioxolan-4-yl)-4-methyl-2-methylthio-5-methoxycarbonyl-1,6-dihydropyrimidine (6) by Biguinelli type reaction is described. The products resulting from the acidic hydrolysis are studied.