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Report | Regular issue | Vol 23, No. 11, 1985, pp.2913-2916
Published online, 1st January, 1970
DOI: 10.3987/R-1985-11-2913
Synthesis of (±)-Lupinine and (±)-Epi-lupinine using Regioselective Alkylation of Functionalized 3-Sulfolene

Takashi Nomoto and Hiroaki Takayama*

*Faculty of Pharmaceutical Sciences, Teikyo University, 1091-1 Suarashi, Sagamiko-machi, Tsukui-gun, Kanagawa 199-0195, Japan

Abstract

The regioselective alkylation of 3-(N,N-dimethylaminomethyl)-3-sulfolene was applied to the synthesis of quinolizidine alkaloids, (±)-lupinine and (±)-epi-lupinine.