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Communication | Regular issue | Vol 23, No. 10, 1985, pp.2499-2503
Published online, 1st January, 1970
DOI: 10.3987/R-1985-10-2499
Structure of Sanggenon O, a Natural Diels-Alder Type Adduct from Chinese Crude Drug "Sang-Bai-Pi" (Morus Root Bark)

Yoshio Hano and Taro Nomura*

*Faculty of Pharmaceutical Sciences, Toho University, 2-2-1, Miyama, Funabashi, Chiba 274-8510, Japan


From an acetone extract of the Chinese crude drug “Sang-Hai-Pi” (Japanese name “Sohakuhi”), the root bark of Morus sp. (Moraceae), a new flavanone derivative was isolated and named sanggenon O, whose structure was shown to be 1 on the basis of spectral and chemical evidence. Sanggenon O (1) is a structural isomer of sanggenon C (2), and was derived from 2 by treatment of an alkaline solution. The compound (1) is regarded biogenetically as a Diels-Alder type adduct of a chalcone derivative and a dehydroprenylflavanone derivative.