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Report | Regular issue | Vol 23, No. 9, 1985, pp.2387-2390
Published online, 1st January, 1970
DOI: 10.3987/R-1985-09-2387
Synthesis of 1,2,3,4,4a,5,10,10a-Octahydro-7-hydroxy-2,4a,5-trimethyl-1,5-ethanobenao[g]quinoline: Bridged Benzomorophan with Antagonist Activity

Mikio Hori,* Tadashi Kataoka, Hiroshi Shimizu, Eiji Imai, and Norihiro Kawamura

*Department of Pharmacognosy, Gifu College of Pharmacy, 6-1 Mitahora-higashi 5-chome, Gifu 502-8585, Japan

Abstract

A synthetic approach has been made for the synthesis of 1,5-ethanobenzo[g]quinolines from 11-substituted 2,6-methano-3-benzazocine. The product showed strong antagonist activity.