Online article for Non-subscribers

Pay per view

Heterocycles has a pay-per-view service for Non-subscribers.
You will be able to directly purchase the full text article through PayPal.
Your purchased Paper can be downloaded after the payment is completed.
An e-mail will be sent the URL to download the paper.
If you have any questions, please contact:

Price: ¥ 4,400 (Yen only)
Period: This Article can be accessed for 7 days.

Report | Regular issue | Vol 23, No. 9, 1985, pp.2327-2333
Published online, 1st January, 1970
DOI: 10.3987/R-1985-09-2327
Palladium-catalyzed Coupling Reaction of Chloropyrazines with Indole

Yasuo Akita, Akira Inoue, Keiko Yamamoto, Akihiro Ohta,* Teruo Kurihara, and Mitsuru Shimizu

*Tokyo University of Pharmacy and Life Science, 1432-1 Horinouchi, Hachioji, Tokyo 192-0392, Japan


The palladium-catalyzed cross-coupling reaction of 2-chloropyrazines with indole was shown to proceed in moderate to good yields, giving 2-(pyrazin-2-yl)indoles. The structure determination of the products was made on the basis of the X-Ray diffraction and 13C-NMR spectroscopic analyses.