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Report | Regular issue | Vol 23, No. 9, 1985, pp.2293-2297
Published online, 1st January, 1970
DOI: 10.3987/R-1985-09-2293
Facile Synthesis of 5H-[1]Benzopyrano[2,3-b]-1,2,3,4-tetrahydropyridin-5-ones

Franco M. Pasutto,* Syrd Abuzar, and Srinivasmurthy Satymurthy

*Faculty of Pharmacy , University of Alberta, Edmonton, Alberta T6G, 2N8, Canada


A facile synthesis of 7-substituted-5H-[1]benzopyrano[2,3-b]-1,2,3,4-tetrahydropyridin-5-ones is described. Catalytic hydrogenation of 7-substituted 5H-[1]benzopyrano[2,3-b]pyridin-5-ones affords the title compounds in greater than 90% yields. Facile, high yield, N1-acetylation is achieved by reaction with acetic anhydride.