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Communication | Regular issue | Vol 23, No. 8, 1985, pp.1925-1928
Published online, 1st January, 1970
DOI: 10.3987/R-1985-08-1925
■ Total Synthesis of Ergot Alkaloid (±)-Fumigaclavine B

Toshiko Kiguchi, Chiyomi Hashimoto, and Ichiya Ninomiya*

*Kobe Women’s College of Pharmacy, Motoyamakita, Higashinad, Kobe, Hyogo 658, Japan

Abstract

The synthetic route developed on the despyrrole analogs of clavines was successfully applied to the first total synthesis of (±)-fumigaclavine B (1) and (±)-isolysergine (2), thus firmly established the structure of the former alkaloid (1).