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Communication | Regular issue | Vol 23, No. 8, 1985, pp.1901-1905
Published online, 1st January, 1970
DOI: 10.3987/R-1985-08-1901
Synthesis of C(3)-Alkyl Cephems

Douglas O. Spry* and Anita R. Bhala

*Lilly Reserach Laboratories, Lilly Corporate Center, Eli Lilly & Company, Indianapolis, IN 46285-4813, U.S.A.

Abstract

C(3)-n-Butyl and n-hexyl cephems have been prepared by the conjugate addition of the appropriate organocuprate to the C(3)-chloro and C(3)-vinyl cephem.