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Report | Regular issue | Vol 23, No. 6, 1985, pp.1465-1469
Published online, 1st January, 1970
DOI: 10.3987/R-1985-06-1465
New Difunctionalaized 4-Nitroisoxazoles from α-Nitroacetophenone Oxime

Rodolfo Nesi,* Stefano Chimichi, Piero Sarti-Fantoni, Annalisa Buzzi, and Donatella Giomi

*CNR, Centro di Studio Sulla Chimica e la Struttura dei Composti Eterociclici e lolo Applicazioni, c/o Dipartimento di Chimica Organica "Ugo Schiff", Università di Firenze, Via Gino Capponi 9, I-50121 Firenze, Italy


The title compound (1) reacted smoothly with the acyl chlorides (2a-d) to give the derivatives (3a-d) which were converted in high yields into the nitroisoxazoles (4a-d), respectively, through a base-induced cyclization.